Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10966448 | Vaccine | 2014 | 7 Pages |
Abstract
Additionally, NS3 antibody responses are raised after natural BTV infection and NS3-based ELISAs are therefore appropriate tools for DIVA testing accompanying the DISA vaccine. To enable DIVA, we developed an experimental NS3 ELISA. Indeed, vaccinated sheep remained negative for NS3 antibodies, whereas seroconversion for NS3 antibodies was associated with viremia after heterologous BTV challenge.
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Authors
Femke Feenstra, Mieke Maris-Veldhuis, Franz J. Daus, Mirriam G.J. Tacken, Rob J.M. Moormann, René G.P. van Gennip, Piet A. van Rijn,