Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10966661 | Vaccine | 2014 | 9 Pages |
Abstract
H. pylori HspC vaccines have the potential to overcome some of the issues preventing the development of a human vaccine against this pathogen: HspC induced protective immunity against H. pylori without addition of an adjuvant and without the induction of a severe inflammatory response. However, complete protection was not obtained so further optimisation of this technology is needed if a human vaccine is to become a reality.
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Authors
Yok Teng Chionh, Arthi Arulmuruganar, Elena Venditti, Garrett Z. Ng, Jia-Xi Han, Claire Entwisle, Ching-Seng Ang, Camilo A. Colaco, Shaun McNulty, Philip Sutton,