Article ID Journal Published Year Pages File Type
10966723 Vaccine 2013 9 Pages PDF
Abstract
► Mice received Matrix-M™, AS03, Alum or FCA, spleen, lymph nodes, and serum were analyzed. ► Immune response compared after vaccination with adjuvanted influenza antigen. ► Matrix-M™ activates innate immune cells, not seen by other investigated adjuvants. ► Splenocyte re-stimulation shows enhanced cytokine response in Matrix-M™ treated mice. ► High antibody levels in mice injected with Matrix-M™- or AS03-adjuvanted vaccine.
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Related Topics
Life Sciences Immunology and Microbiology Immunology
Preview
Immune enhancing properties of the novel Matrix-M™ adjuvant leads to potentiated immune responses to an influenza vaccine in mice
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