Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10966859 | Vaccine | 2012 | 6 Pages |
Abstract
⺠Influenza vaccine strains contain variant PB1 genes. ⺠Targeted mutagenesis of PR/8 PB1 can improve vaccine strain characteristics. ⺠Specific PB1 mutations enhance growth of poorly growing virus. ⺠Specific PB1 mutations increase protein yield in allantoic fluid at early time points.
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Authors
Ewan P. Plant, Teresa M. Liu, Hang Xie, Zhiping Ye,