Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10967033 | Vaccine | 2013 | 8 Pages |
Abstract
⺠Standard and type 1 polarized DCs were compared for use in cancer immunotherapy. ⺠Type 1 polarized DCs (αDC1 and mDC) induced superior T cell functionality. ⺠CCR7-dependent migration of type 1 polarized DCs was influenced by autocrine CCL19. ⺠Maturation with MPLA, IFN-γ and PGE2 (mpDC) proved to be less optimal.
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Authors
Morten Hansen, Gertrud Malene Hjortø, Marco Donia, Ãzcan Met, Niels Bent Larsen, Mads Hald Andersen, Per thor Straten, Inge Marie Svane,