Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10967120 | Vaccine | 2013 | 7 Pages |
Abstract
The low responses observed in patients receiving a single dose suggest the need to emphasize adhesion to vaccination protocols to avoid failure. The CD4/CD8 ratio may be considered as an immune status marker which could help to better choose the moment of vaccination. Our findings underscore the importance of identifying strategies that optimize the timing and effectiveness of hepatitis A vaccination in HIV-infected patients and of the need for further studies on individual factors such as sex and hepatitis C co-infection that may affect the response to vaccination. Likewise, the sub-optimal effectiveness of three doses of 720 EU in the rapidly accelerated schedule, if confirmed in future studies, might lead to a revision of the current schedule recommended for HIV-infected travellers.
Keywords
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Immunology and Microbiology
Immunology
Authors
Guillermo Mena, Alberto L. GarcÃa-Basteiro, Anna Llupià , Consolación DÃez, Josep Costa, Josep-MarÃa Gatell, Felipe GarcÃa, José-MarÃa Bayas,