Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10967268 | Vaccine | 2014 | 7 Pages |
Abstract
In the majority of scenarios explored, partially effective vaccines lead to 50% or greater reductions in the number of cases. This is true even of vaccines that we would not expect to proceed to licensure due to poor or incomplete immune responses. Our results show that a partially effective vaccine can have significant impacts on serotype distribution and mean age of cases.
Keywords
Related Topics
Life Sciences
Immunology and Microbiology
Immunology
Authors
Isabel Rodriguez-Barraquer, Luis Mier-y-Teran-Romero, Ira B. Schwartz, Donald S. Burke, Derek A.T. Cummings,