| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10967339 | Vaccine | 2012 | 6 Pages |
Abstract
⺠Immunization with Ad5 [E1-, E2b-] results in antigen specific immune induction in Ad5 immune NHP. ⺠Vaccination with Ad5 [E1-, E2b-]-SIV resulted in significant viral control as compared to controls. ⺠Immune responses were induced to a second pathogen, H1N1, in the hyper Ad5 immune NHP. ⺠Ad5 [E1-, E2b-] platform is effective regardless of pre-existing and concomitant vector immunity.
Related Topics
Life Sciences
Immunology and Microbiology
Immunology
![Control of SIV infection and subsequent induction of pandemic H1N1 immunity in rhesus macaques using an Ad5 [E1-, E2b-] vector platform](/preview/png/10967339.png "First Page Preview: Control of SIV infection and subsequent induction of pandemic H1N1 immunity in rhesus macaques using an Ad5 [E1-, E2b-] vector platform")
Authors
Elizabeth S. Gabitzsch, Joseph P. Balint-Junior, Younong Xu, Stephanie Balcaitis, Brigitte Sanders-Beer, Julie Karl, Kent J. Weinhold, Slobodan Paessler, Frank R. Jones,