Article ID Journal Published Year Pages File Type
10967419 Vaccine 2012 6 Pages PDF
Abstract
► Constrained and unconstrained nicotine haptens generate differential immune responses. ► Vaccination of constrained hapten CNI with ALUM showed protective effects in rats. ► High antibody concentration was found to be crucial in conferring protective effects. ► Nicotine analgesia is a rapid assay to probe vaccination effects.
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Related Topics
Life Sciences Immunology and Microbiology Immunology
Preview
Probing the protective effects of a conformationally constrained nicotine vaccine
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