Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10967488 | Vaccine | 2013 | 7 Pages |
Abstract
⺠HBsAgS VLP inhibit plasmacytoid DC function, but not conventional DC. ⺠HBsAgS VLP access MHCI antigen presentation pathways both in vitro and in vivo. ⺠HBsAgS VLP access MHCII antigen presentation pathways both in vitro and in vivo. ⺠Inclusion of a helper T cell epitope did not enhance CTL killing. ⺠CD8+ DC are responsible for cross-presentation of HBsAgS VLP associated antigen.
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Authors
Jessica M. Moffat, Wan-Shoo Cheong, José A. Villadangos, Justine D. Mintern, Hans J. Netter,