Article ID Journal Published Year Pages File Type
10967488 Vaccine 2013 7 Pages PDF
Abstract
► HBsAgS VLP inhibit plasmacytoid DC function, but not conventional DC. ► HBsAgS VLP access MHCI antigen presentation pathways both in vitro and in vivo. ► HBsAgS VLP access MHCII antigen presentation pathways both in vitro and in vivo. ► Inclusion of a helper T cell epitope did not enhance CTL killing. ► CD8+ DC are responsible for cross-presentation of HBsAgS VLP associated antigen.
Related Topics
Life Sciences Immunology and Microbiology Immunology
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