Article ID Journal Published Year Pages File Type
10967536 Vaccine 2012 10 Pages PDF
Abstract
► We fused HMy2 cells with ex vivo haematological tumour cells in vitro. ► The fusions generated a panel of stable, self replicating hybrid cell lines. ► The hybrid cell lines induced tumour-specific cytotoxic T cell responses in vitro. ► HMy2/tumour hybrid cell lines represent candidate cancer vaccines.
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Related Topics
Life Sciences Immunology and Microbiology Immunology
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In vitro evaluation of human hybrid cell lines generated by fusion of B-lymphoblastoid cells and ex vivo tumour cells as candidate vaccines for haematological malignancies
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