| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10967611 | Vaccine | 2012 | 9 Pages |
Abstract
⺠We tested a MHC I/peptide single chain DNA vaccine against Listeria infection in mice. ⺠This approach was designed to optimize antigen presentation to CD8+ T cells. ⺠Kd/LLO single chain DNA vaccine elicited CD8+ T cells and reduced bacterial loads. ⺠Helper T cell responses improved memory but not primary anti-bacterial responses. ⺠Single chain approaches should be considered as part of a composite vaccine.
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Immunology
Authors
Sojung Kim, Adam Zuiani, Javier A. Carrero, Ted H. Hansen,