Article ID Journal Published Year Pages File Type
10967637 Vaccine 2013 6 Pages PDF
Abstract
► We predicted and identified HLA-A*0201-restricted CTL epitope from ZnT8. ► We utilized it to immunize HLA-A2.1/Kb transgenic (Tg) mice. ► The peptides could elicit specific CTLs in vitro, and induce diabetes in mice. ► The peptides could have therapeutic potential in preventing of T1D.
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Related Topics
Life Sciences Immunology and Microbiology Immunology
Preview
Identification of novel HLA-A*0201-restricted cytotoxic T lymphocyte epitopes from Zinc Transporter 8
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