Article ID Journal Published Year Pages File Type
10967752 Vaccine 2012 8 Pages PDF
Abstract
► We demonstrate the immune enhancement of a tailored N. caninum vaccine in mice. ► Vaccine antigen was selected based on its capacity to activate dendritic cells. ► Vaccines with Providean-AVEC® adjuvant limited N. caninum infection. ► A tenth of the antigen payload was needed compared to other aqueous adjuvants. ► Protective responses against N. caninum entailed systemic IgG2a and IFN-γ.
Related Topics
Life Sciences Immunology and Microbiology Immunology
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