Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10967752 | Vaccine | 2012 | 8 Pages |
Abstract
⺠We demonstrate the immune enhancement of a tailored N. caninum vaccine in mice. ⺠Vaccine antigen was selected based on its capacity to activate dendritic cells. ⺠Vaccines with Providean-AVEC® adjuvant limited N. caninum infection. ⺠A tenth of the antigen payload was needed compared to other aqueous adjuvants. ⺠Protective responses against N. caninum entailed systemic IgG2a and IFN-γ.
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Authors
Florencia Celeste Mansilla, Olga LucÃa Franco-Mahecha, MarÃa Ángeles Lavoria, DadÃn Prando Moore, Adrián Nicolás Giraldez, Marcela Elvira Iglesias, Maximiliano Wilda, Alejandra Victoria Capozzo,