| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10967760 | Vaccine | 2012 | 8 Pages |
Abstract
⺠CD8+ T cell memory can be produced independent of the signal 3 mediators type I IFN and IL-12. ⺠IFN/IL-12 independent T cell memory is compromised in the absence of the TNF receptors CD27 and OX40. ⺠CD27/OX40 are non-cytokine signal 3 mediators of CD8+ T cell immunity. ⺠Combined TLR/CD40 vaccination elicits IFN/IL-12 independent, CD27/OX40-dependent immunity.
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Authors
Phillip J. Sanchez, Ross M. Kedl,