Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10967766 | Vaccine | 2012 | 10 Pages |
Abstract
⺠PspA is a candidate vaccine antigen against pneumococcal disease. ⺠Certain individuals susceptible to pneumococcal infection have ccl5 polymorphisms. ⺠These variances limit expression of CCL5, which is needed for pneumococcal immunity. ⺠We show HTL responses to PspA199-246 are largely resistant to CCL5 deficiency.
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Immunology
Authors
Rajesh Singh, Shailesh Singh, David E. Briles, Dennis D. Taub, Susan K. Hollingshead, James W. Jr.,