Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10967769 | Vaccine | 2012 | 7 Pages |
Abstract
⺠We fabricated antigen-loaded dissolving microneedle array (dMNA) using chondroitin sulfate as a base. ⺠The dMNAs penetrated, dissolved and released the antigen into the skin of mice, and then induced antigen-specific antibody responses efficiently. ⺠Antigen-loaded dMNA is a promising antigen-delivery system for percutaneous vaccination.
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Authors
Seishiro Naito, Yukako Ito, Tomoko Kiyohara, Michiyo Kataoka, Masaki Ochiai, Kanji Takada,