| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10967771 | Vaccine | 2012 | 10 Pages |
Abstract
⺠Dose effects of lactobacilli on T cell responses to rotavirus vaccine were studied. ⺠Low dose promoted Th1 and down-regulated Treg cell responses in gnotobiotic pigs. ⺠High dose increased natural and induced Treg cells and their TGF-β/IL-10 production. ⺠Dose effects were similar in the intestinal and systemic lymphoid tissues of the pigs. ⺠The same probiotic strain at different doses exerted qualitatively different effects.
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Authors
Ke Wen, Guohua Li, Tammy Bui, Fangning Liu, Yanru Li, Jacob Kocher, Lin Lin, Xingdong Yang, Lijuan Yuan,