Article ID Journal Published Year Pages File Type
10967786 Vaccine 2012 7 Pages PDF
Abstract
► Gas vesicles (Gv) display Chlamydia proteins as part of their membrane structures. ► Recombinant gas vesicles (r-Gv) are readily recognized by human immune sera. ► Gv engage TLRs and stimulate proinflammatory cytokines in a peptide-specific manner. ► Temporal degradation of Gv in vitro, culminates in antigen display at cell surface. ► R-Gv promise to be an ideal multisubunit vaccine display/delivery platform.
Related Topics
Life Sciences Immunology and Microbiology Immunology
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