Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10967786 | Vaccine | 2012 | 7 Pages |
Abstract
⺠Gas vesicles (Gv) display Chlamydia proteins as part of their membrane structures. ⺠Recombinant gas vesicles (r-Gv) are readily recognized by human immune sera. ⺠Gv engage TLRs and stimulate proinflammatory cytokines in a peptide-specific manner. ⺠Temporal degradation of Gv in vitro, culminates in antigen display at cell surface. ⺠R-Gv promise to be an ideal multisubunit vaccine display/delivery platform.
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Authors
Tawanna S. Childs, Wilmore C. Webley,