| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10967787 | Vaccine | 2012 | 7 Pages |
Abstract
⺠The DNA vaccine BCR-ABL/GM-CSF/IL-12/dSLIM prevents Ph+ ALL in syngeneic mice. ⺠DNA vaccination induces an innate and adaptive immune response. ⺠DNA vaccination eliminates minimal residual disease of Ph+ ALL in syngeneic mice. ⺠Compared to 6-MP the DNA vaccine led to a significantly longer leukemia-free survival. ⺠Synergistic treatment of minimal residual disease with DNA vaccination and 6-MP.
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Immunology
Authors
Joachim Köchling, Yvonne Rott, Stefanie Arndt, Christina Marschke, Manuel Schmidt, Burghardt Wittig, Katrin Kalies, Jürgen Westermann, Günter Henze,