| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10967802 | Vaccine | 2012 | 7 Pages |
Abstract
⺠We constructed rSmeg_pMIP_(bfpA or intimin) and rBCG_pMIP_(bfpA or intimin) vectors. ⺠The vectors contain the bfpa and intimin encoding genes. ⺠The vectors are stable, replicate and express BfpA and intimin. ⺠Vectors induce effective immune response measured by specific antibody and cytokines. ⺠The antibodies block in vitro enteropathogenic E. coli adhesion to epithelial cells. ⺠The constructed recombinant BfpA and intimin vectors are promising vaccines.
Related Topics
Life Sciences
Immunology and Microbiology
Immunology
Authors
Halyka Luzorio Franzotti Vasconcellos, Karina Scaramuzzi, Ivan Pereira Nascimento, Jorge M. Jr., Cecilia M. Abe, Roxane M.F. Piazza, Andre Kipnis, Wilmar Dias da Silva,