Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10967833 | Vaccine | 2012 | 9 Pages |
Abstract
⺠A glycan placed on the perimeter of the gp120 CD4bs restricts antibody access. ⺠Adjuvant Quil A modulates antibody fine specificity. ⺠Adjuvant Quil A promotes antibody responses to the CD4-binding site. ⺠The elicited CD4bs antibody titers are too low to achieve significant neutralizing activity.
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Immunology
Authors
Fatima K. Ahmed, Brenda E. Clark, Dennis R. Burton, Ralph Pantophlet,