Article ID Journal Published Year Pages File Type
10967833 Vaccine 2012 9 Pages PDF
Abstract
► A glycan placed on the perimeter of the gp120 CD4bs restricts antibody access. ► Adjuvant Quil A modulates antibody fine specificity. ► Adjuvant Quil A promotes antibody responses to the CD4-binding site. ► The elicited CD4bs antibody titers are too low to achieve significant neutralizing activity.
Related Topics
Life Sciences Immunology and Microbiology Immunology
Authors
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