Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10967909 | Vaccine | 2012 | 6 Pages |
Abstract
⺠T. gondii GRA7 was a prominent vaccine antigen against toxoplasmosis. ⺠The recombinant plasmids of pEGFP-GRA7 and pET30-GRA7 were constructed. ⺠A heterologous DNA prime-protein boost enhanced humoral and Th1 immune responses to GRA7. ⺠Mice immunized with DNA prime-protein boost regime showed significant survival rate.
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Authors
Juan Min, Daofeng Qu, Changzheng Li, Xilin Song, Qunli Zhao, Xin-ai Li, Yongmei Yang, Qi Liu, Shenyi He, Huaiyu Zhou,