Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10967933 | Vaccine | 2012 | 19 Pages |
Abstract
⺠Corticosteroids, cytokines and maternal antibodies affect neonatal immune responses. ⺠Non-rodent, non-umbilical cord blood models of neonatal immune function are needed. ⺠Cells and soluble mediators of adult and neonatal immune systems differ in quantity. ⺠Passive antibodies in adult animal models do not inherently suppress B cell responses. ⺠Vaccines must be optimized for use in neonates.
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Authors
Douglas C. Hodgins, Patricia E. Shewen,