| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10967937 | Vaccine | 2012 | 11 Pages |
Abstract
⺠Inter-species divergence between P. falciparum and P. reichenowi is comparable to housekeeping genes. ⺠A signature of purifying selection was detected in the proenzyme and enzyme domains. ⺠No strong evidence for positive selection was detected for SNPs in the non-repeat regions. ⺠Biased geographical distribution was observed in SNPs and in the haplotypes of the OR and SR regions. ⺠Significant genetic differentiation was detected for SNPs and OR- and SR-haplotypes among parasite populations.
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Authors
Kazuyuki Tanabe, Nobuko Arisue, Nirianne M.Q. Palacpac, Masanori Yagi, Takahiro Tougan, Hajime Honma, Marcelo U. Ferreira, Anna Färnert, Anders Björkman, Akira Kaneko, Masatoshi Nakamura, Kenji Hirayama, Toshihiro Mita, Toshihiro Horii,