Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10968005 | Vaccine | 2012 | 9 Pages |
Abstract
⺠The extent of PCV effect on carriage determines indirect protection. ⺠PCV7 is licensed as a 4-dose regimen (3 + 1), but shorter regimens are often adopted. ⺠We show that a reduced schedule (2 + 1) results in nasopharyngeal carriage reduction. ⺠3 + 1 and 2 + 1 schedules showed differences in PCV7-type carriage corrected by booster. ⺠We found that 2-dose 2nd-year catch-up campaigns may enhance carriage reduction.
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Authors
Ron Dagan, Noga Givon-Lavi, Nurith Porat, David Greenberg,