Increased efficacy of an adenovirus-vectored foot-and-mouth disease capsid subunit vaccine expressing nonstructural protein 2B is associated with a specific T cell response

Article ID	Journal	Published Year	Pages	File Type
10968018	Vaccine	2011	10 Pages	PDF

Abstract

âº We constructed Ad5-O1C vectors to examine their efficacy against FMDV in bovines. âº Ad5-O1C construct with full length viral 2B coding region was most efficacious. âº The enhanced protected correlated with an enhanced T cell response.

Keywords

Foot-and-mouth disease virus T cell response

Related Topics

Life Sciences Immunology and Microbiology Immunology

Preview

Increased efficacy of an adenovirus-vectored foot-and-mouth disease capsid subunit vaccine expressing nonstructural protein 2B is associated with a specific T cell response

Authors

Mauro Pires Moraes, Fayna Diaz-San Segundo, Camila C. Dias, Lindomar Pena, Marvin J. Grubman,