| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10968089 | Vaccine | 2012 | 6 Pages |
Abstract
⺠Structural perturbation of diphtheria toxoid occurs upon adsorption to aluminium hydroxide. ⺠Five physicochemical techniques are used to characterize adsorbed diphtheria toxoid. ⺠Adsorption causes an increase of β-sheet content and a decrease of α-helix content in the toxoid. ⺠Analytical methods offer a tool to demonstrate consistency in the production of diphtheria toxoid.
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Authors
Marie Régnier, Bernard Metz, Wichard Tilstra, Coenraad Hendriksen, Wim Jiskoot, Willem Norde, Gideon Kersten,