| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10968099 | Vaccine | 2012 | 6 Pages |
Abstract
⺠Generated two formats of recombinant flagellin-HA vaccines targeting 3 H5N1 HPAIV. ⺠The vaccines protect ferrets against a lethal A/Vietnam/1203/04 challenge. ⺠The vaccines protect mice against a lethal A/Indonesia/5/05 challenge. ⺠Both R3.HA5 and R3.2xHA5 elicit robust long-lasting HAI antibody responses to HPAIV. ⺠The R3.2xHA5 format vaccines are more immunogenic than the R3.HA5 in mice.
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Authors
Ge Liu, Langzhou Song, Lucia Reiserova, Umang Trivedi, Hong Li, Xiangyu Liu, Diana Noah, Fuxiang Hou, Bruce Weaver, Lynda Tussey,