Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10968101 | Vaccine | 2012 | 6 Pages |
Abstract
⺠A novel DNA vaccine encoding GAPDH (pCgap) was constructed. ⺠A significant antibody response against GAPDH was generated and antibodies to the pCgap DNA vaccine were bactericidal. ⺠The DNA vaccine induced both Th1 and Th2 immune responses, but the IgG1 response was greater than the IgG2a response. ⺠The DNA vaccine pCgap provided protective efficacy against the H. parasuis challenge.
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Authors
Shulin Fu, Minmin Zhang, Jiwen Ou, Huazhen Liu, Chen Tan, Jinlin Liu, Huanchun Chen, Weicheng Bei,