Article ID Journal Published Year Pages File Type
10968116 Vaccine 2012 9 Pages PDF
Abstract
► Heterologous vaccination against cancer is more immunogenic than homologous. ► Early regulatory T cell suppression is the key to enhanced antigen-specific CTL. ► Heterologous vaccination improves the efficacy of Treg-modulating E. coli vaccine. ► Heterologous vaccination against cancer in the therapeutic setting is feasible.
Keywords
Related Topics
Life Sciences Immunology and Microbiology Immunology
Preview
Early Treg suppression by a listeriolysin-O-expressing E. coli vaccine in heterologous prime-boost vaccination against cancer
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