Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10968141 | Vaccine | 2011 | 8 Pages |
Abstract
⺠In this study, we immunized mice with the bacterial molecules SADH(E) and SADH(S). ⺠These molecules carry a sequence similar to the 6H4 anti-prion epitope. ⺠The immunization elicited anti-prion Abs and attenuated prion disease in mice. ⺠Antigenic mimicry-based prion vaccines might be a new type of prion vaccine.
Keywords
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Immunology
Authors
Daisuke Ishibashi, Hitoki Yamanaka, Tsuyoshi Mori, Naohiro Yamaguchi, Yoshitaka Yamaguchi, Noriyuki Nishida, Suehiro Sakaguchi,