Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10968151 | Vaccine | 2011 | 9 Pages |
Abstract
⺠First report of a clinical trial of a vaccine to prevent Ross River virus disease. ⺠Vero cell culture-derived inactivated RRV vaccine is safe and well tolerated. ⺠Three doses of a 2.5 μg aluminum hydroxide-adjuvanted formulation is optimal. ⺠Induces antibody titers associated with protection from disease in >90% of subjects. ⺠Data suggest that vaccine will effectively prevent Ross River virus disease.
Keywords
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Immunology
Authors
Gerald Aichinger, Hartmut J. Ehrlich, John G. Aaskov, Sandor Fritsch, Christiane Thomasser, Wolfgang Draxler, Michael Wolzt, Markus Müller, Fritz Pinl, Pierre Van Damme, Annick Hens, Jack Levy, Daniel Portsmouth, Georg Holzer, Otfried Kistner,