| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10968182 | Vaccine | 2011 | 5 Pages |
Abstract
⺠This review analyses why so many randomised therapeutic vaccine trials have failed to confirm the optimism of single centre phase 2 studies. ⺠Focussing on a few example vaccine trials reveals a number of different possible explanations. ⺠The success rate of future studies could be improved by excluding “inflammatory” phenotypes (by Biomarkers) as well as by combination with different modalities, such as radiotherapy and chemotherapy.
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Authors
Angus G. Dalgleish,