Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10968225 | Vaccine | 2011 | 12 Pages |
Abstract
⺠BRSV-ISCOMs induce strong clinical and virological protection in young conventional calves with BRSV-specific maternal antibodies. ⺠Protection is associated with local and systemic humoral responses as well as T cell responses dominated by IFNγ production. ⺠Animals that did not shed virus detectable by PCR or cell culture following challenge possessed particularly high levels of pulmonary IgA.
Related Topics
Life Sciences
Immunology and Microbiology
Immunology
Authors
Sara Hägglund, Kefei Hu, Karin Vargmar, Lesly Poré, Ann-Sophie Olofson, Krister Blodörn, Jenna Anderson, Parvin Ahooghalandari, John Pringle, Geraldine Taylor, Jean-François Valarcher,