| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10968282 | Vaccine | 2011 | 10 Pages |
Abstract
⺠Significant associations were found with class I HLA-B (p = 0.05) as well as class II HLA-DPB1 (p = 0.01) and -DPA1 (p = 0.03) genes for measles vaccine-induced antibody levels after the second dose. ⺠Second dose of measles vaccine overcomes HLA restriction through an as yet unknown mechanism. ⺠Class I and class II HLA molecules may act as restriction elements for the recognition of measles virus peptides by human T cells.
Keywords
IgGCPMRPMIIQRrSCAHistocompatibility antigens class IISSPSequence-specific primerHuman leukocyte antigenHLAenzyme immunoassayimmunoglobulin GImmunogeneticsEIAReference Strand Conformation AnalysisAntibody formationstimulation indexcounts per minuteAnti-HBsLymphocyte activationinterquartile rangeRoswell Park Memorial Institute mediummillilitersplaque forming unitinternational unitsMeasles vaccineMeasles–mumps–rubella vaccinepfucurie
Related Topics
Life Sciences
Immunology and Microbiology
Immunology
Authors
Robert M. Jacobson, Inna G. Ovsyannikova, Robert A. Vierkant, V. Shane Pankratz, Gregory A. Poland,