Article ID Journal Published Year Pages File Type
10968308 Vaccine 2011 7 Pages PDF
Abstract
► In this study crosslinked rStxB induced protective immune response. ► Initially it was humoral immune response which switches to cell mediated after 3rd dose as observed by IgG isotyping. ► Cytokine production suggests that rStxB could be effective for induction of mixed Th type of immune response. ► IFN-γ and IL-4 were detected in the supernatants of the cultures of rStxB stimulated splenocytes. ► Histopathology of kidney of vaccinated and unimmunized animals was also conducted.
Related Topics
Life Sciences Immunology and Microbiology Immunology
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