Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10968308 | Vaccine | 2011 | 7 Pages |
Abstract
⺠In this study crosslinked rStxB induced protective immune response. ⺠Initially it was humoral immune response which switches to cell mediated after 3rd dose as observed by IgG isotyping. ⺠Cytokine production suggests that rStxB could be effective for induction of mixed Th type of immune response. ⺠IFN-γ and IL-4 were detected in the supernatants of the cultures of rStxB stimulated splenocytes. ⺠Histopathology of kidney of vaccinated and unimmunized animals was also conducted.
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Authors
Pallavi Gupta, Manglesh Kumar Singh, Yamini Singh, Vandana Gautam, Subodh Kumar, Om Kumar, Ram Kumar Dhaked,