Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10968347 | Vaccine | 2012 | 6 Pages |
Abstract
⺠CctA is a new toxin of Clostridium chauvoei belonging to the β-barrel pore forming toxins. ⺠Antibodies against rCctA fully neutralize cytotoxic and haemolytic activity of C. chauvoei ⺠Vaccination of guinea pigs with recombinant CctA induces protection against myonecrosis. ⺠Data show that CctA is the major toxin and main virulence factor of C. chauvoei.
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Authors
Joachim Frey, Anders Johansson, Sibylle Bürki, Edy M. Vilei, Keith Redhead,