Article ID Journal Published Year Pages File Type
10968352 Vaccine 2012 8 Pages PDF
Abstract
► Immunization with naturally evolving env genes, given sequentially, is promising. ► Motif-optimized env sequences were superior to wild type for neutralizing antibodies. ► Simultaneous boosting with DNA and protein at different sites enhanced antibodies. ► Antibodies that neutralized heterologous HIV-1 isolates were obtained in rabbits.
Related Topics
Life Sciences Immunology and Microbiology Immunology
Authors
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