Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10968356 | Vaccine | 2012 | 8 Pages |
Abstract
âºVero-derived whole-virus H5N1 vaccine induces long-lasting humoral and cellular immunity. ⺠One or two priming immunizations provide long-term protection against wild-type H5N1 challenge. ⺠Humoral and cellular immunity substantially increased by homologous or heterologous booster. ⺠Broadest protection provided by heterologous prime-boost immunization regimen.
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Authors
Nicolas Sabarth, Helga Savidis-Dacho, Michael G. Schwendinger, Peter Brühl, Daniel Portsmouth, Brian A. Crowe, Otfried Kistner, P. Noel Barrett, Thomas R. Kreil, M. Keith Howard,