Article ID Journal Published Year Pages File Type
10968380 Vaccine 2012 10 Pages PDF
Abstract
► HIV-1 Tat raises an adjuvant-free antibody response depending on Tat oligomerization. ► Adjuvanticity is a T-cell dependent phenomenon in which a Th2 profile predominates. ► Three model antigens become adjuvant-free immunogenic when coupled to fragment Tat1-57 or Tat37-57. ► Tat1-57 and Tat37-57 might represent an alternative to the adjuvants in vaccination.
Related Topics
Life Sciences Immunology and Microbiology Immunology
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