Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10968380 | Vaccine | 2012 | 10 Pages |
Abstract
⺠HIV-1 Tat raises an adjuvant-free antibody response depending on Tat oligomerization. ⺠Adjuvanticity is a T-cell dependent phenomenon in which a Th2 profile predominates. ⺠Three model antigens become adjuvant-free immunogenic when coupled to fragment Tat1-57 or Tat37-57. ⺠Tat1-57 and Tat37-57 might represent an alternative to the adjuvants in vaccination.
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Immunology
Authors
Adeline Gadzinski, Delphine Matz, Emilie Favre, Michel Léonetti,