Evaluation of a new serological technique for detecting rabies virus antibodies following vaccination

► A new method (ECL test) using electro-chemi-luminescence labels and carbon electrode plateswas evaluated for detecting rabies virus antibody. ► By using a cutoff point of 0.15 IU/ml, the ECL test demonstrated 100% sensitivity and 95% specificity for human samples, and 96% sensitivity and 95% specificity for field animal samples. ► The preliminary results appear promising and demonstrate a higher sensitivity than traditional ELISA methods.