| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10968441 | Vaccine | 2011 | 8 Pages |
Abstract
⺠Natural products (NPs) are potential source of immune activating/repressing compounds. ⺠This review briefly summarizes the role of pattern recognition receptors (PRR) in modulating immunity. ⺠It discusses NPs as source of compounds that modulate immunity via PRRs. ⺠It proposes a new conceptual approach to identify potential vaccine adjuvants within collections of NPs.
Keywords
muramyl dipeptideToll-interleukin-1 receptorPGNGalCeriDCsRLRsmoDCsMDPCLRsNLRsNOD1NPLsCRDEpigallocatechin-3-gallateEGCGNB-LRRnucleotide-binding oligomerization domain 1HTSFLS2AdjuvantsNPspDCsalpha-galactosylceramideTIRDendritic cellsimmature dendritic cellshigh throughput screeningNatural productsSlippathogen associated molecular patternsPeptidoglycanpattern recognition receptorsC-type lectin receptors
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Authors
Jose Rey-Ladino, Allen G. Ross, Allan W. Cripps, Donald P. McManus, Ronald Quinn,