Article ID Journal Published Year Pages File Type
10968453 Vaccine 2011 8 Pages PDF
Abstract
► We investigated the protective efficacy of rHSP70 against lethal Salmonella infection. ► Results revealed that HSP70 immunization significantly increased IgG1 and IgG2a. ► Lymphocyte proliferation, Th2 and Th1 cytokines were also increased significantly. ► HSP70 was found to be immunogenic and protective even without adjuvants. ► Immunization of rHSP70 conferred 70-90% protection against Salmonella infection.
Related Topics
Life Sciences Immunology and Microbiology Immunology
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