| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10968509 | Vaccine | 2013 | 6 Pages |
Abstract
⺠We assessed the secular trends in diagnostic code density during 2001-2009. ⺠An increasing trend in diagnostic code density was observed across all sites. ⺠Sudden changes were observed when changes in coding policies or data inclusion criteria took place. ⺠Inappropriate historical comparator may introduce a false positive association between a vaccine and an adverse event. ⺠Ongoing monitoring of the diagnostic code density may provide guidance on choice of study design and comparison groups.
Related Topics
Life Sciences
Immunology and Microbiology
Immunology
Authors
Rulin C. Hechter, Lei Qian, Lina S. Sy, Sharon K. Greene, Eric S. Weintraub, Allison L. Naleway, Ali Rowhani-Rahbar, James G. Donahue, Matthew F. Daley, Gabriela Vazquez-Benitez, Marlene M. Lugg, Steven J. Jacobsen,