| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10968565 | Vaccine | 2012 | 8 Pages |
Abstract
⺠Vaccines based on capsular polysaccharides protect against most meningococcal disease. ⺠Glycoconjugate vaccines improve polysaccharide immunogenicity providing protection in infants. ⺠SBA level is the established correlate of protection used to license polysaccharide vaccines. ⺠Novel vaccines based on protein antigens designed to improve coverage are undergoing licensure. ⺠SBA is proposed as the correlate of protection for protein antigens but remains to be validated.
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Immunology
Authors
Caroline Vipond, Rory Care, Ian M. Feavers,