Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10968593 | Vaccine | 2011 | 7 Pages |
Abstract
⺠The APCH1 scFv molecule targets antigens to SLA II bearing cells in vitro. ⺠The APCH1 molecule works as an excellent immunoadjuvant in pigs in DNA immunization protocols. ⺠pCMV-APCH1PQ induces non-neutralizing antibodies and SLA II-restricted T-cell responses. ⺠The immune responses induced by pCMV-APCH1PQ do not protect pigs against ASFV challenge.
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Authors
J.M. Argilaguet, E. Pérez-MartÃn, C. Gallardo, F.J. Salguero, B. Borrego, A. Lacasta, F. Accensi, I. DÃaz, M. NofrarÃas, J. Pujols, E. Blanco, M. Pérez-Filgueira, J.M. Escribano, F. RodrÃguez,