| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10968605 | Vaccine | 2011 | 6 Pages |
Abstract
⺠The duration of BCG-induced tuberculin skin-test sensitisation was determined in neonatally vaccinated calves. ⺠BCG induced strong skin-test sensitisation in calves but this sensitisation waned rapidly after 6 months. ⺠Groups of BCG vaccinated calves that had lost or retained their skin-test response after 6-months were challenged with M. bovis to investigate the relationship between skin-test sensitisation and vaccine induced protective immunity. ⺠Loss of BCG induced skin-test responsiveness did not result in loss of protective immunity against M. bovis infection.
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Authors
A.O. Whelan, M. Coad, B.L. Upadhyay, D.J. Clifford, R.G. Hewinson, H.M. Vordermeier,