| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10968620 | Vaccine | 2011 | 8 Pages |
Abstract
⺠Mice were immunized with recombinant enolase. ⺠High levels of IgG1 and IgG2a were induced in immune serum. Killing capacity of neutrophils enhanced after yeasts were opsonized with anti-serum. Fungal burdens reduced after antibody were passive transferred. ⺠Both Th1 cytokine IL-12 and Th2 cytokine IL-10 increased in immune serum. ⺠Enolase can effectively protect against systemic infection caused by two strains of Candida albicans differing in virulence in mice.
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Authors
Wen qing Li, Xu chu Hu, Xiaohuan Zhang, Yanping Ge, Sainan Zhao, Yan Hu, Robert B. Ashman,