Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10968724 | Vaccine | 2012 | 10 Pages |
Abstract
⺠Influenza A virus replication was impaired by silent mutations in the NP gene. ⺠Influenza A virus containing silently mutated NP gene was attenuated in mice. ⺠This may represent a novel strategy for development of live attenuated vaccine.
Related Topics
Life Sciences
Immunology and Microbiology
Immunology
Authors
Darisuren Anhlan, Eike-Roman Hrincius, Christoph Scholtissek, Stephan Ludwig,